Cryptosporidium parvum is a single-celled small intestine parasite of the genus Cryptosporidium.
Cryptosporidium parvum triggers cryptosporidiosis, a zoonosis that is mainly transmitted by mammals. Disease symptoms include:
Cholangitis (inflammation of the bile ducts)
Pancreatitis (inflammation of the pancreas)
Cryptosporidium parvum occurs worldwide and colonizes the small intestine of humans and various mammals such as dogs, cats, cattle, sheep, and pigs. Infectious oocysts (spores) of the pathogen show high resistance to disinfectants such as chlorine.
Relevance of pathogen in transmission in endoscopy
Pulmonology: Not relevant
Ear, nose, and throat: Not relevant
Urology: Not relevant
Relevance for endoscope surveillance
High concern organism
Cryptosporidium parvum is transmitted by the fecal–oral route via contaminated water or food, as well as via contact infections.
Resistance to antibiotics
Cryptosporidium parvum shows low susceptibility to many antimicrobial agents.
Barbee SL et al. Inactivation of Cryptosporidium parvum oocyst infectivity by disinfection and sterilization processes, Gastrointest. Endosc. 1999 May; 49(5):605-11.
Campbell I et al. Effect of disinfectants on survival of Cryptosporidium oocysts, Vet Rec. 1982 Oct 30;111(18):414–5.
Gries O/Ly T. Infektologie – Kompendium humanpathogener Infektionskrankheiten und Erreger, Springer-Verlag Berlin Heidelberg 2019.
Kryptosporidiose, Robert Koch-Institut, https://www.rki.de/DE/Content/Infekt/EpidBull/Merkblaetter/Ratgeber_Kryptosporidiose.html (accessed on 7/30/2021).