Elizabethkingia meningoseptica is a Gram-negative rod-shaped bacterium named after its discoverer, microbiologist Elizabeth O. King. The pathogen was also previously classified as Flavobacterium and Chryseobacterium.
Elizabethkingia meningoseptica is responsible for an increasing number of nosocomial infections, which are affecting neonatal wards and dialysis patients in particular. The pathogen can cause the following, among others:
Cholangitis (inflammation of the bile ducts)
Endocarditis (inflammation of the heart’s inner lining)
Elizabethkingia meningoseptica is widespread in nature, e.g., in soil or fresh and salt water. The pathogen has also been found in frogs and fish.
Relevance of pathogen in transmission in endoscopy
Gastroenterology: Not relevant
Ear, nose, and throat: Not relevant
Relevance for endoscope surveillance
Low or moderate concern organism
The route of transmission is still largely unknown. Sources of infection include tap water, hospital devices, parenteral nutrition solutions, or contaminated venous catheters.
Resistance to antibiotics
Elizabethkingia meningoseptica is multi-resistant to antibiotics commonly used against Gram-negative pathogens, including beta-lactam agents. The pathogen produces two beta-lactamases:
ESBL (extended-spectrum beta-lactamases)
Class B carbapenem-hydrolyzing metallo-beta-lactamases
Elizabethkingia meningoseptica also shows resistance to aminoglycosides, tetracyclines, and chloramphinicol.
Elisabethkingia, Centers for Disease Control and Prevention, https://www.cdc.gov/elizabethkingia/index.html (accessed on 07.15.2021).
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